On this square stand many significant monuments of Perugia: the Gothic Cathedral of San Lorenzo built between 1345 and 1490, with the Loggia by Braccio Fortebraccio.

In the centre of the square stands The Fontana Maggiore, one of the most famous fountains in Italy and the Palazzo dei Priori which houses the National Gallery of Umbria (outside visit). This museum is a testimony to the many different regional forms of art, such as wooden and iron sculptures, paintings, and also silverware and fabric design. We continue on to Bastia Umbria or another nearby locality where we will stop for lunch. Our itinerary continues on with a visit to Assisi, located on the top of Mount Subasio. With the tour guide we will visit the Gothic Basilica of S. Chiara, and then Piazza Comunale considered to be the city centre. Here stand the ruins of the famous temple dedicated to the Goddess Minerva, and the Basilica of S. Francesco, one of the most famous Christian sanctuaries in the world. The Basilica is divided into two sections connected by a staircase – the Romanic lower church with the crypt and the relics of Saint Francis and the Gothic upper church where frescoes by Giotto and Cimabue can be viewed. Our itinerary continues onwards to Santa Maria degli Angeli. Here we will visit the Basilica, a Renaissance building which preserves the cupola designed and built by Alessi and where we can find the Porziuncola, the rural chapel where San Francis founded the Franciscan order in the 1209. Dinner and overnight stay in Assisi or nearby.